Explore what DNA sequencing measures and how its scope differs from selected-marker testing. Compare methods around a specific question rather than a promise of completeness.
Sequencing can cover selected regions, an exome, or a broader genome, depending on the test. The guides in this trail explain the importance of stated scope, measurement quality, and interpretation. When reading a test description, separate what the instrument measures from what the report chooses to analyze. Then ask which regions and types of variation might be difficult to assess. This approach makes technical specifications more useful without assuming that a larger dataset will always provide a more definite answer.
Follow the articles below in the order that fits your question. Each includes further reading and links into the broader Geneomix field guide, so you can move between an overview and a more detailed explanation without losing the context.
Whole genome and exome sequencing differ in the DNA they examine, but breadth alone does not determine what a report can explain. Learn how test design, interpretation, family information, and reporting choices shape the usefulness and limits of each approach.
Genotyping and sequencing can both describe genetic differences, but they collect information in different ways. Learn how selected markers, sequence reads, coverage, and imputation shape the results, and which questions make a method comparison useful rather than confusing.
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